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This selective toxicity is likely due to the enhanced copper ion enrichment in cancer cells (16)

As previously stated in this review, GSH is the most abundant intracellular antioxidant and plays major roles in the antioxidant defense system and maintenance of redox homeostasis in both the PNS and CNS (Aoyama K, 2021)

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Through rigorously designed randomized controlled trials and multi-center studies, the efficacy and safety of TCM can be objectively assessed, providing a scientific basis for its inclusion in standard treatment protocols

Suitability of 3D human brain spheroid models to distinguish toxic effects of gold and poly-lactic acid nanoparticles to assess biocompatibility for brain drug delivery