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Insufficient ATP production by the mitochondria and nutrient depletion activate the AMP-activated protein kinase (AMPK) [253], which initiates autophagy by phosphorylating and activating the components of the autophagy-activating protein complex and inhibiting the activity of mTORC1
doi: 10.1007/s11255-018-1801-5
10.1016/j.cell.2020.04.027 60
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[DOI] [PubMed] [Google Scholar] 80.Wu C.H., Lu F.H., Chang C.S., Chang T.C., Wang R.H., Chang C.J
