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Here it should be considered that the measured level of NADPH does not necessarily reflect the flux through G6PD or the rate of production of NADPH but simply reflects the concentration of NADPH at equilibrium
Interleukin-6 (IL-6) is the predominantly cytokine released by CAFs in response to the activation of the signal transducer and activator of transcription 3 (STAT3) via HIF-1

Moss et al., 2016)

If the mouse failed to escape within 3 min, it was placed inside the escape box

Methylation is a typical epigenetic mechanism that suppresses gene expression [171]
