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MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded in the mitochondrial genome, first identified in research published in Cell Metabolism in 2015

One key group includes individuals with pernicious anemia, an autoimmune condition that affects the bodys ability to absorb vitamin B12 from food

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[166] : 54 On 6 February ahin, Treci and Rosenbaum together with Tom Madden and Chris Barbosa from Acuitas Therapeutics met with PEI who were happy with what BioNTech proposed, with the only point of contention being that PEI rejected BioNTech's proposal to either skip toxicology studies altogether or run them in parallel with clinical trials before human trials could begin

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