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Aldophosphamide is cleaved to phosphoramide mustard and acrolein, and it is phosphoramide which induces the antitumoral effect

Through bulk and single-cell transcriptomics, chromatin accessibility profiling, and functional studies, we reveal that Glutathione Peroxidase 2 orchestrates lineage commitment by regulating key transcription factors, leading to emergence of multilineage liver and intestinal progenitors

M., Weigand, G

doi: 10.1126/sciadv.adi4462 49 ChenY.ChenZ.WangH.CuiZ.LiK
