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Organotypic brain slice cultures are a useful tool to study neurological disease, providing a more complex 3-dimensional system than standard 2-dimensional in vitro cell culture

doi: 10.1126/scisignal.2004652 85 LeeHJZhuangGCaoYDuPKimHJSettlemanJ

Additionally, heating the culture supernatant for 30 minutes at 121 C caused the rate of AFB1 degradation to increase to 84.76 %, demonstrating that extracellular proteins or enzymes were effectively degrading AFB1

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