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Glutathione is a vital antioxidant and detoxifier, essential for maintaining cellular health and protecting against oxidative stress

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Tumor-associated macrophages (TAMs), which are infiltrating macrophages in tumor tissues, can be divided into M1-type macrophages that inhibit tumor growth and M2-type macrophages that promote tumor growth

doi:10.1177/0960327113506723 Joshi EM, Heasley BH, Macdonald TL (2009) 2-ABT-S-oxide detoxification by glutathione S-transferases A1-1, M1-1 and P1-1: implications for toxicity associated with zileuton

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