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PPARa contributes to neuronal ferroptosis by regulating the FSP1-CoQ10-NAD(P)H pathway through its transcriptional activity To elucidate the specific mechanism by which PPARa regulates FSP1, we constructed stable cell lines with either over-expression or knockdown of PPARa using lentiviral vectors

Given the wide availability of anti-RA drugs that only prove effective after several cycles, prior individualized target screening to guide treatment choice, particularly through aOoC technology, would enable faster and more precise evaluation of therapeutic response and support a more personalized approach to disease management

Chronic Vagus Nerve Stimulation Reverses Heart Rhythm Complexity in Patients With DrugResistant Epilepsy: An Assessment With Multiscale Entropy Analysis. Epilepsy & Behavior 83: 168174

Retatrutide is the only late-stage compound that provides significant glucagon receptor activation alongside GLP-1 and GIP agonism
