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The mice were injected with B-017 (0.8 mg kg 1 BW in 50 l NaCl) or the negative control peptide (0.8 mg kg 1 BW in 50 l NaCl) intracardially 5 min before reperfusion and intraperitoneally (1.6 mg kg 1 BW in 50 l NaCl) on day 1, day 3, day 5 and day 7 post infarction
Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage
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Asp is also the precursor of four essential amino acids (methionine, threonine, lysine, and isoleucine)
10.1053/j.gastro.2005.11.046 Gastroenterology 112 RaspiniB.ProsperiM.GuiducciL.SantocchiE.TancrediR.CalderoniS.et al (2021)
