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Studies have also examined it in models involving neuropathic and metabolic stress responses

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10.1002/prca.200900076 15 BlangerM.AllamanI.MagistrettiP

Studies report modulation of NO synthase activity and interaction with NO-mediated tissue protection pathways, which may underlie its broad cytoprotective profile

The fact that PE serves to counter this process and that ferroptosis lipid peroxidation specifically is targeted to PE phospholipids suggests that removal of the buffering effect of PE on lipid integrity may be a key aspect of ferroptosis