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Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion article deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion

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This reduction in enzymatic activity and compromised ROS detoxification might contribute to an elevated oxidative stress environment within the cell (Mirsadraee and Saadat, 2019)

Interestingly, we found that pretreatment of BT474 parental cells with RSL3 alone for twenty-four hours decreases the number of persister cells remaining after subsequent lapatinib treatment (Fig

Halliwell B, Cheah IK & Drum CL (2016) Ergothioneine, an adaptive antioxidant for the protection of injured tissues