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Inadequate synthesis or intake can lead to serious metabolic disorders, which may result in fatal outcomes

doi: 10.1111/bjh.14459

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10.1016/j.ajem.2004.06.001 Sztajnkrycer MD: Valproic acid toxicity: overview and management

Conclusion Collectively, the current study implied that supplementation of multistrain/multispecies synbiotic (250 mg/day) concomitant with L-carnitine (2 500 mg/day) for 8 weeks resulted in greater amendment in anthropometric and glycemic indices, and HDL-C in healthy female individuals with obesity without any severe side effects, indicating that L-carnitine + synbiotic co-supplementation seems to be more beneficial to ameliorate the mentioned parameters, compared with L-carnitine individual therapy