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A pharmacologic strategy for overcoming poor BBB permeability and/or efflux out of the brain of organic acid-based, small molecule therapeutics such as NAC is co-administration with a targeted or nonselective membrane transporter inhibitor

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Background Arsenic is a major environmental toxin that is detoxified in the liver by biochemical mechanisms that are still under study

Results In this study, we developed a multifunctional nanoparticle of polydopamine-platinum (PDA@Pt) to combat acute gout by leveraging mild hyperthermia to synergistically enhance UA degradation and anti-inflammatory effect

Learn how sermorelin sleep therapy promotes deeper rest by restoring natural growth hormone levels at night.