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Therefore, clinicians especially dermatologists must be aware of this sign so that such cases may be diagnosed and treated early

In addition, tumour bed biopsies that did not contain tumour cells were associated with a significantly lower recurrence rate compared with those with tumour cells (Mller and Kessler, 2018)

Reduces inflammation and swelling, helping to alleviate pain and discomfort

It is thought to act as a -aminobutyric acid agonist that increases satiety, although the precise mechanism of action is unclear

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