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Trimethylamine n-Oxide (TMAO) modulates the expression of cardiovascular Disease-Related MicroRNAs and their targets

Data from nerve conduction velocities, sympathetic skin responses in the palms and soles, skin biopsies, and intraepidermal nerve fiber densities showed that neurotoxic treatment causes typical small fiber neuropathy with reduced intraepidermal nerve fiber density (IENFD) and reduced C-fiber conduction velocity

H., Cantello, R

Consistent use of an appropriate amount will yield the best results over time

Supplements impact the skin, positively or negatively, in one of two ways: altering the chemistry in one of our skin-organ axes (like the gut-skin axis, liver-skin axis, nervous system-skin axis, etc.) or traveling from our gut, into our blood, then to our skin where they directly impact the skin tissue itself or the skin microbiome