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HMGCS2-Induced Autophagic Degradation of Tau Involves Ketone Body and ANKRD24

2000, BRISTOL-MYERS SQUIBB COMPANY, EU, EP 0 646 646 B1 Huang XB, Cyrille D, Thomas P, Bulmus V: Synthesis of Hetertelechelic polymers with affinity to glutathione-s-transferase and biotin-tagged proteins by RAFT polymerization and thiol-ene reactions

For the injection, the microcapsules are suspended in an aqueous injection vehicle containing carboxymethylcellulose or d-mannitol and Tween 20

Translating those results to humans would require crossing several large gaps: different species, different molecule, different delivery route, and different endpoints