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Inhibition of hydrogen sulfide synthesis reverses acquired resistance to 5-FU through miR-215-5p-EREG/TYMS axis in colon cancer cells

doi: 10.1021/tx500256j

During seizures, the excessive neuronal excitability is closely linked to the energy support provided by astrocytes to neurons, known as the ANLS [185]

Indeed, GDF11 was shown to signal more effectively and induce a greater SMAD3-dependent signal through all type 1 receptors than MSTN, and substitution of the residues in the wrist helix of the MSTN type 1 interface with those of GDF11 significantly enhanced the potency of MSTN by improving the stability of the interaction between the prehelix loop and wrist helix 25

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