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Because colchicine has high anti-proliferative activity and promising clinical prospects, many colchicine analogues have been synthesized to avoid adverse effects 53

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Glial functions in the blood-brain communication at the circumventricular organs

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However, high-dose niacin (as a medication for cholesterol) is generally not recommended during breastfeeding, because significant amounts could enter milk and cause unwanted effects in the nursing infant (flushing, for example)

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Additionally, carbon nanotubes are widely used carbon-based NPs that are composed of graphite sheets rolled into tubes having diameter in the nanometers range [237]

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