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Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation

Courade JP, Besse D, Delchambrec, et al

While the pathways are well elucidated and the fine details of their molecular mechanisms are beyond the scope of this manuscript, it is worth noting that not all patients suffer the same fate when it comes to APAP ingestion and hepatotoxicity
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Dis Esophagus 25(7):614-22, 2012