cysteine glutathione synthesis is the substrate for the intracellular of Glutathione: Overview of its protective

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These cells stimulate the recruitment of additional effector cells such as cytotoxic T cells and NK cells, which contribute to tissue injury through direct cytotoxicity or the release of proinflammatory cytokines and chemokines such as TNF, IL-1, IL-2, IL-12, IL-17, IFN-, CCL2, CCL3, CCL4, and CCL5

Endogenous and exogenous reactive oxygen species, such as superoxide anion, hydroxyl radical, hypohalite radical, and hydrogen peroxide, and reactive nitrogen species, such as nitric oxide, peroxynitrite, and nitrite, play a major role in the airway inflammation and are determinants of asthma severity

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10.1007/s13346-024-01538-5