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Indeed, the extrinsic apoptosis pathway, activated by death receptors, is crucial for cellular apoptosis

Mitochondria cannot manufacture glutathione de novo , so glutathione is synthesized in the cytosol and a small fraction of the total cellular pool is then imported into the mitochondrial matrix by carrier-mediated transport (22

Chen, TianfengJournal of Materials Chemistry B: Materials for Biology and Medicine (2018), 6 (4), 568-579CODEN: JMCBDV

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References: Kang et al
