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While AOD-9604 does not stimulate cell proliferation (no IGF-1 elevation), the precautionary principle applies for active malignancies

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Publisher's Note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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They are especially valuable in protocols that demand collagen stimulation without inducing inflammation

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Theoretical concerns about telomerase activation Because epitalon influences telomerase activity and gene expression, theoretical concerns exist about potential unintended consequences such as abnormal cell proliferation

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