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A subsequent study identified the compound N-(4-(2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)phenyl)acetamide as a notable SARM1 inhibitor, which demonstrated significant efficacy in a mouse model of CIPN (Fig

A dose of 100 mcg daily for six or seven days should be administered by intramuscular or deep subcutaneous injection

Combining intramuscular treatments can complicate recovery and confuse the cause of a reaction

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Jeschke MG, Barrow RE, Herndon DN
