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The naturally occurring LA form is the R-enantiomer which is also an essential cofactor involved in certain mitochondrial enzyme complex functions, whereas synthetic LA is a racemic mixture of both R- and S-forms in which the R-enantiomer is found more biologically active than the S-enantiomer

Archived from the original on May 9, 2019

Conversely, promoter mutated at ARE site did not respond to SFN, validating the SFN-mediated restoration of Nrf2/ARE signaling

Many genes involved in salt stress response are inducible expression type, while most transgenic plants are obtained by using constitutive promoters to drive the continuous expression of target genes, which may cause unexpected side effects

Increased expression of GPX4 was also detected in high-risk patients