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In those with an insidious course, depending on the nature and amount of damage to the kidney, symptoms such as high blood pressure, chronic fatigue, weakness, night-time urination, foul breath, increased need to drink water, and edema of the legs may occur

Clinical trial registration: clinicaltrials.gov as NCT02517476 (registered 7 August 2015) This secondary analysis is based on the randomized-controlled EFFORT trial, which compared individualized nutritional therapy with usual care in medical inpatients at nutritional risk

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