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Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: evidence for direct involvement of claudins in tight junction barrier

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The investigators conducted a multicenter, double-blind, placebo-controlled, active-controlled phase 3a trial (ClinicalTrials.gov ID: NCT05567796) evaluating the efficacy and safety of the combination of semaglutide and cagrilintide in adults without diabetes with a body-mass index (BMI) of greater than or equal to 30 or greater than or equal to 27 with at least one obesity-related complication

Your physician reviews these factors before recommending a treatment plan, not the other way around

doi: 10.1016/0092-8674(94)90006-x