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Nudge metabolism toward burn downstream of higher NAD/sirtuins, cells often show higher energy expenditure signals

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Using ionizing radiation-induced senescent IMR90 cells, it was observed that FOXO4 maintains senescent cell viability by targeting p53 to the nucleus and preventing it from inducing apoptosis

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Ectopic expression of perilipin A, as expected, increases the storage of TAG by inhibiting hydrolysis (15, 127)
