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This may be why its use is still viewed as controversial in the U.S

Geniposide alleviates neuropathic pain in CCI rats by inhibiting the EGFR/PI3K/AKT pathway and ca2+ Channels

Washington, DC, USA: 2006

However, mitochondria seem to be mainly affected by this toxin, leading to increased production of oxidative agents, and disturbance of energy metabolism of oligodendrocytes with subsequent cell death

The most important question is this one
