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Consequently, oxidative stress acts not only as an initial trigger in vitiligo but also as a catalyst that, by generating autoantigens and inflammatory cytokines, perpetuates autoimmune responses and drives disease progression 17,46

However, in recent years, dedifferentiation, senescence and other forms of cell death, such as autophagy, pyroptosis and ferroptosis, have been found to be involved in the loss of cells

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In some cases, injuries can set off an attack of gout

The acetaminophen blood concentration drawn four hours after the overdose was substantially elevated at 1243 (upper end of therapeutic range 66199) mol/L