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doi: 10.1016/j.molcel.2016.06.030

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633635 A recently developed transgenic AD mice model with amyloid and neurofibrillary tangles pathology (ADLP APT mice) manifested altered gut microbiota, chronic intestinal inflammation, increased intestinal barrier permeability, and systemic inflammation

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demonstrated that VDR colocalizes with Np63 at MED1-marked super-enhancer regions, cooperatively driving the mesenchymal lineage commitment of epidermal stem cells
