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Neural upregulation Neuroendocrine pathways, such as the sympathetic nervous system and the hypothalamus-pituitary-adrenal (HPA) axis, oversee the bodys inflammatory responses

ATP depletion activates ER stress (ERS) pathways [69, 70], leading to misfolded protein aggregation and redox imbalance if unresolved

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In this pathway, GPX4 also serves as a crucial regulator of ferroptosis
[DOI] [PMC free article] [PubMed] [Google Scholar] 198.Fine JM, Stroebel BM, Faltesek KA, Terai K, Haase L, Knutzen KE, et al
