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The period from 2008 to 2013 yielded a pivotal discovery with the identification of the cGAS-STING pathway as the cytosolic DNA sensor, which provided the core molecular explanation for this association (Fig

4.5 Urogenital system The symptoms of PACS patients in the urogenital system include renal function decline, sexual dysfunction, and decreased sperm count

2025 Apr 15:693:137611

Natural products, as well as semi-synthetic and synthetic analogs, are being actively investigatedbased on the premise that structural modifications may yield compounds with superior properties compared to their natural counterparts

The latest findings derived from large-scale longitudinal clinical data highlight the importance of distinguishing between two forms of autism exhibiting different developmental trajectories and polygenic architectures depending on the age at diagnosis [137]