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The acetylation of this specific locus was maintained even in limited acetyl-CoA conditions when NFAT was constitutively active, which suggest that acetyl-CoA levels might not be rate limiting for site-specific histone acetylation

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and Malignancy

Because nerve regenerative capacity declines with age and comorbidities elevate oxidative stress, treatment effects may attenuate in older or metabolically compromised patients

Futur J Pharm Sci 10 , 106 (2024)

In this review, we focus on the regulation of the transsulfuration pathway pertaining to cysteine and H 2 S, which could be targeted to develop novel therapeutics