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Description
As fat cells expand, they begin to produce more NNMT, an enzyme that disrupts normal metabolic function
Pharm Genom
This includes both behavioral and biochemical mechanisms
This suggests either these types of reactions do not occur by some function of the higher dosage, that they do occur but are mitigated by close consideration of electrolyte balance and/or other variables, or that they do occur but are simply not reported
Efficacy should be hedged accordingly the trials tell us what the drug does in a controlled trial population, not what any individual using research material will experience
