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[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Keshani M., Alikiaii B., Askari G., Yahyapoor F., Ferns G.A., Bagherniya M

General SLE Meds Anifrolumab Azathioprine Belimumab Cyclophosphamide Typically reserved for severe manifestations, such as CNS or kidney Hydroxychloroquine: Staple of lupus treatment Shown to modify disease progression in SLE and to prevent flares Recommended for all patients with systemic lupus Methotrexate Mycophenolate Local or systemic glucocorticoids for acute exacerbations Lupus Nephritis Therapies Systemic steroids Azathioprine, PO Belimumab Cyclophosphamide Mycophenolate, PO BID Calcineurin inhibitors: Tacrolimus Voclosporin Disease activity measures: Goal is remission or low lupus disease activity Encourage regular clinical and lab monitoring by a rheumatologist Routine labs include CBC with differential, C3/C4, dsDNA, Cr, urinalysis with microscopic urine protein:creatinine Lupus is an independent risk factor for cardiovascular disease

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