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Psychiatry 28 , 564578 (2023)

Keays R, Harrison P, Wendon J, Forbes A, Gove C, Alexander G, Williams R (1991)

3.7.3 Environmental resilience and metabolic synergy Survival and delivery are optimized through distinct physiological traits

Neurons rely heavily on mitochondrial energy production, and in AD, early defects in mitochondrial dynamics, respiratory chain activity, and calcium buffering impair synaptic function and render neurons more vulnerable to stress
