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One theory proposed for the development of the TSAb is that there is a defect in suppressor T cells that allows helper T cells to stimulate B cells to produce thyroid autoantibodies

Virology 299 , 122132 (2002)

doi:10.1152/physrev.00043.2008 Torre C, Camacho M, Liu SY, Huon LK, Capasso R

