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In line, the antihyperglycemic drug metformin which activates AMP-activated protein kinase (AMPK) but blocks mTOR signaling (and thereby glycolysis) and which also inhibits the OXPHOS cycle by interfering with the electron transport chain interfered with both -glucan- and oxLDL-induced trained immunity of monocytes (Keating et al., 2020)
The residue was washed with 20 mL of pure water and 20 mL of methanol, dried using an aspirator, suspended in pure water and benzene and stirred for 5 min
2023 Jun;14(3):1424-1440
doi: 10.1016/j.seizure.2012.02.011
Kannt et al
