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GSH neutralizes reactive oxygen and nitrogen species, supports the activity of antioxidant enzymes like glutathione peroxidases (GPx) and glutathione S-transferases (GST), prevents irreversible protein oxidation through glutathionylation, and participates in detoxification through conjugation [47]

[DOI] [PMC free article] [PubMed] [Google Scholar] 182.Larson JM

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Redox regulation of cJun DNA binding by reversible Sglutathiolation

GSH and the immune system In addition to its function as an intracellular redox buffer, GSH plays a key role in the immune system and in the antiviral and inflammatory response