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I believe that the quality of the injections is very important for maximum possible benefit
10.1016/j.tcb.2012.10.006 Trends Cell

Some protocols suggest a 2:1 ratio, alternating between two B12 shots and one lipotropic injection per week for maximum benefit [3]

acnes strains producing more porphyrins in response to B12 while health-associated strains did not (Johnson, 2016, UCLA)
Adsorption behavior of poly(dimethyl-diallylammonium chloride) on pulp fiber studied by cryo time-of-flight secondary ion mass spectrometry and cryo-scanning electron microscopy
