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[DOI] [PMC free article] [PubMed] [Google Scholar] 417.Sharma S, Kelly TK, Jones PA

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In the Phase 2 obesity trial, retatrutide 12 mg produced approximately 24.2% mean weight loss at 48 weeks ( Jastreboff et al., NEJM 2023 ), and the Phase 2 type 2 diabetes trial showed strong HbA1c and weight reductions ( Rosenstock et al., Lancet 2023 )