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Description
G6PD , glucose-6-phosphate dehydrogenase
For 78c, the most important interaction in the active site appears to be a hydrophobic interaction of C4 group and Trp176 and the hydrogen bond between the 2-ketoresidue and the side chain amide of Asp183 [78]
[DOI] [PMC free article] [PubMed] [Google Scholar] 682
This is often done in clinical settings to ensure higher absorption levels
Initially, this regulatory mechanism attracted attention in the context of tumor immunomodulation
