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H 2 O 2 induced oxidative stress in OFs, reflected by a dose-dependent increase in GSSG, a known measure of cell response to ROS ( Figure 1 )
Jaga K, Dharmani C (2007) The interrelation between organophosphate toxicity and the epidemiology of depression and suicide
Recent studies have proposed that the antidepressant esketamine obstructs NMDA receptors on GABAergic neurons, leading to the disinhibition of glutamatergic neurons, thereby inducing a rapid increase in glutamatergic signaling within the mPFC [28-30]
doi: 10.1038/npp.2014.168
Kim K, Hur Y, Ryu E-K, Rhim J-H, Choi CY, Baek C-M, et al
