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Int J Mol Sci (2021) 22(8):3998
Abbreviations COVID-19: Novel coronavirus disease 2019 IL-6: Interleukin-6 G-CSF: Granulocyte colony-stimulating factor TNF-: Tumor necrosis factor- MSCs: Mesenchymal stem cells hWJCs: Human umbilical cord Whartons jelly-derived mesenchymal stem cells GVHD: Graft-versus-host disease CRP: C-reactive protein RT-PCR: Real-time polymerase chain reaction CT: Computerized tomography GGO: Ground-glass opacity FBS: Fetal bovine serum RCD: Regulated cell death References Zu ZY, Jiang MD, Xu PP, Chen W, Ni QQ, Lu GM, et al

Growth-inhibitory effect of a novel synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, on ovarian carcinoma cell lines not dependent on peroxisome proliferator-activated receptor-gamma expression

However, it remains unclear, what precisely affected the development of the oxidative stress-induced apoptosis while changing the level of Grx5 (overexpression or knockout of the gene): alterations of the thioldisulfide homeostasis or homeostasis of the ironsulfur clusters

FAK-Paxillin Pathway: It activates the focal adhesion kinase (FAK) pathway, which is essential for cell migration and attachment, allowing repair cells to anchor to the site of damage and begin rebuilding
