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Similarly, the percentage of CD86 + RAW264.7 macrophages markedly increased following MnUA exposure (Fig

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Consistently, the induction of profibrotic genes ( Col1a1, Col3a1, Fn1, Eln, Ccn2, and Acta2 ) and kidney injury markers ( Ngal, Kim-1 ) following UUO was blunted in Usp2 KO mice (Fig
