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The study was approved by the Animal Research Committee of Shanghai Jiao Tong University

As the period of clinical manifestation of the disease generally occurs on average 20 to 38 days after the calf has contact with the pathogen, blood was collected on a fixed date of 20 days after inoculation (60 days of experiment) to maintain equal inoculation days among animals

As for anticancer lipids, sphingosine 1-phosphate decreases ATC migration, while activation of estrogen receptor and restrains PTC progression [300]

"Randomized clinical trial to comparing the efficacy of daily, weekly and monthly administration of vitamin D3"

Therefore, researchers are actively investigating the potential of NNMT inhibitors such as 5-amino-1MQ in experimental models