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Mechanistically, acetylating Lys403 sterically hinders the NADP + from entering the NADP + structural site, which reduces the stability of the enzyme

Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial

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In this study, we developed cell lines with comparable expression levels of the three major MDR ABC transporters (ABCB1, ABCC1, and ABCG2)