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The early signs and symptoms of arthritis in the legs include pain, swelling, stiffness, decreased range of motion, trouble
According to a study published in PubMed Central (NIH), IV administration of vitamin B12 provides a faster increase in B12 levels compared to oral supplementation, making it a potentially better option for patients with severe deficiency

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Metformin, widely prescribed for type 2 diabetes, can impair B12 absorption through effects on calcium-dependent ileal uptake
