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doi: 10.2337/dc10-1076 Jain M, Ngoy S, Sheth SA, Swanson RA, Rhee EP, Liao R, Clish CB, Mootha VK, and Nilsson R ( 2014 )
Dr Wartolowska said: Not all people develop these changes as they age, but they are present in more than 50% of patients over the age of 65 and most people over the age of 80 even without high blood pressure, but it is more likely to develop with higher blood pressure and more likely to become severe. [] The researchers found that a higher load of WMH was strongly associated with current systolic blood pressure, but the strongest association was for past diastolic blood pressure, particularly when under the age of 50

As a result, it remains unclear whether combining these peptides provides additional benefits or alters their overall safety profile

10.1016/S0278-6915(03)00218-7 64

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