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Kornic PA, Harty MMJ, Grant JA

FIGURE 31 The relationship between dose and effect can be separated into pharmacokinetic (dose-concentration) and pharmacodynamic (concentration-effect) components

Intestinal Permeability Regulation by Tight Junction: Implication on Inflammatory Bowel Diseases

GSH synthesis is regulated by the availability of glutamate cysteine ligase (GCL) [16], which in turn is regulated by TGF1, which decreases GCL expression, such that high TGF1 levels lead to reduced GSH production [16]

The formulation specifically combines 50mg of GHK-Cu (Copper Tripeptide-1), 10mg of BPC-157 (Body Protection Compound), and 10mg of TB-500 (a synthetic Thymosin Beta-4 fragment), yielding a total molecular peptide weight of 70mg per unit